Reaction of hydroxyl-protected derivatives of hydroxyalkoxyamines (3a, b, c) with either 4, 6- dichloro-2, 5-diformamidopyrimidine (5) or 4, 6-dichloro-5-formamidopyrimidine (31) and subsequent cyclization of the resultant 6-(alkoxyamino) pyrimidines (6, 17, 32, 35) by heating with diethoxymethyl acetate afforded 9-alkoxy-6-chloropurines (7, 18, 33, 36), which were converted subsequently to 9-(3-hydroxypropoxy)-and 9-[3-hydroxy-2-(hydroxy- ...