e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Synthesis and preliminary evaluation of 2-substituted-1, 3-benzoxazole and 3-[(3-substituted) propyl]-1, 3-benzoxazol-2 (3H)-one derivatives as potent anticancer …
Abstract The synthesis and cytotoxic activity studies of a new series of cyclic amine containing benzoxazole and benzoxazolone derivatives are described. The 2-cyclic amine- 1, 3-benzoxazoles 5a–k, 5-chloro-3-(3-chloropropyl)-1, 3-benzoxazol-2 (3 H)-one 8 and 3-[3- (cyclic amino) propyl]-1, 3-benzoxazol-2 (3 H)-ones 9a–f were synthesized. The newly synthesized compounds with the influence of the presence of cyclic amine moiety in the ...