Synthesis and activity of selective MMP inhibitors with an aryl backbone

…, HS Shieh, R Stegeman, AM Stevens, CI Villamil

Index: E. Barta, Thomas; P. Becker, Daniel; J. Bedell, Louis; A. De Crescenzo, Gary; J. McDonald, Joseph; E. Munie, Grace; Rao, Shashi; Shieh, Huey-Sheng; Stegeman, Roderick; M. Stevens, Anna; I. Villamil, Clara Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 24 p. 2815 - 2817

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Citation Number: 31

Abstract

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... A series of novel, MMP-1 sparing arylhydroxamate sulfonamides with activity against MMP-2 and -13 is described. ... Individual members of the matrix metalloproteinase (MMP) family of zinc-dependent enzymes catalyze a variety of important physiological processes, such as tissue ...