Helvetica chimica acta

Cobalt??Catalyzed Carbonylation of N??Alkylbenzaldimines to 'N??Alkylphthalimidines'(= 2, 3??Dihydro??1H??isoindol??1??ones) via Tandem C H Activation and …

JK Funk, H Yennawar, A Sen

Index: Funk, Jeffrey K.; Yennawar, Hemant; Sen, Ayusman Helvetica Chimica Acta, 2006 , vol. 89, # 8 p. 1687 - 1695

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Citation Number: 22

Abstract

Abstract The reaction of N-alkylbenzaldimines with carbon monoxide (CO) in the presence of cobalt (Co) catalysts resulted in the formation of N-alkylphthalimidines (Table 1). Their formation is proposed to occur by C [BOND] H activation of the aryl ring, migratory insertion of the hydride species into the benzaldimine functionality, CO coordination, and insertion into the Co [BOND] C bond, followed by reductive elimination of the N-alkylphthalimidine ...