One-pot synthesis of N-alkyl substituted phosphoryl guanidines

…, WP Macedo, MCM Silva, GCO Ramos…

Index: Costa De Souza, Marcos; Pires De Macedo, William; Campos M. Da Silva, Marcelo; Costa De O. Ramos, Guilherme; Alt, Helmut G. Phosphorus, Sulfur and Silicon and the Related Elements, 2004 , vol. 179, # 6 p. 1047 - 1054

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Citation Number: 9

Abstract

This article describes an attractive and one-pot synthesis of the title compound by phosphorylation of just prepared N-substituted guanidines from cyanamide and the desired amine. The method allows a variety of N-substituents to hang on the final phosphoryl guanidine as a function of the wider availability of commercial simple amines.