β-Amino esters were obtained in up to 78% yield with 72: 28–96: 4 diastereomeric ratios by the reaction of the chiral titanium enolate of menthyl esters, prepared using the TiCl4/Et3N reagent system with prochiral imines. A representative syn-β-amino ester derivative has been used for the resolution of racemic mandelic acid to obtain a sample with> 99% ee in a single step. A representative syn-β-amino ester was converted to the corresponding N- ...
