Journal of the American Chemical Society

Syntheses in the 5, 8-Dihydroxyquinaldine Series

A Burger, GT Fitchett

Index: Burger; Fitchett Journal of the American Chemical Society, 1953 , vol. 75, p. 1359,1361

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Citation Number: 7

Abstract

Only few derivatives of 5, 8-dihydroxyquinoline have become known which contain functional groups associated with special physiological properties. For example, no dialkylaminoalkylaminoquinoline carrying hydroxyl groups in positions 5 and 8 has been described] in spite of the possible significance of such substitutions for the Schonhofer theory of antimalarial action of aminoquino-1ines. I This study contributes to the chemistry ...