Ruthenium/TFA-catalyzed coupling of activated secondary propargylic alcohols with cyclic 1, 3-diones: Furan versus pyran ring formation

V Cadierno, J Díez, J Gimeno…

Index: Cadierno, Victorio; Diez, Josefina; Garcia-Garrido, Sergio E.; Gimeno, Jose; Nebra, Noel Advanced Synthesis and Catalysis, 2006 , vol. 348, # 15 p. 2125 - 2132

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Citation Number: 45

Abstract

A catalytic system consisting of the 16-electron allyl-ruthenium (II) complex [Ru (η3-2- C3H4Me)(CO)(dppf)][SbF6](dppf= 1, 1′-bis (diphenylphosphino) ferrocene) and trifluoroacetic acid (TFA) has been used to promote the coupling between secondary propargylic alcohols and cyclic 1, 3-diketones. The nature of the resulting products was found to be dependent on the ring size of the dicarbonyl compound employed. Thus, ...