Russian journal of general chemistry

Synthesis and aminomethylation of 2-isobutyl-3-and 4-diethoxyphosphorylmethylfurans

LM Pevzner

Index: Pevzner Russian Journal of General Chemistry, 2006 , vol. 76, # 7 p. 1063 - 1068

Full Text: HTML

Citation Number: 1

Abstract

Abstract Synthetic procedure for preparing 2-isobutyl-3-and 4-furancarboxylic acyl chlorides is developed. Reduction of these compounds with lithium alumohydride leads to corresponding alcohols which under treating with thionyl chloride in the presence of pyridine form chloromethyl derivatives. The latter compounds are phosphorylated with sodium diethyl phosphite under the Michaelis-Becker reaction conditions to give corresponding ...