Synthesis and Evaluation of Hybrid Bis??cationic Salts as Antimalarial Drugs

…, R Escale, A Pellet, H Vial, Y Vo??Hoang

Index: Ortial, Stephanie; Denoyelle, Severine; Wein, Sharon; Berger, Olivier; Durand, Thierry; Escale, Roger; Pellet, Alain; Vial, Henri; Vo-Hoang, Yen ChemMedChem, 2010 , vol. 5, # 1 p. 52 - 55

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Citation Number: 6

Abstract

Malaria is one of the most common diseases and is caused by protozoan parasites of the genus Plasmodium. The World Health organization (WHO) estimates that 3 billion people live in areas where malaria transmission occurs. Indeed, it is endemic in 109 countries and territories in tropical and subtropical regions, particularly in sub-Saharian Africa. Each year, malaria affects∼ 300 million people worldwide and causes between 1 and 1.5 million ...