Regiospecific allylic mono-and dibromination of 4-methoxy-1, 1, 1-trihalo-3-alken-2-ones and 5-methoxy-1, 1, 1, 2, 2-pentafluoro-4-hexen-2-one, and their …

…, RA Freitag, S Brondani, W Cunico, HG Bonacorso…

Index: Martins, Marcos A. P.; Sinhorin, Adilson P.; Da Rosa, Adriano; Flores, Alex F. C.; Wastowski, Arci D.; Pereira, Claudio M. P.; Flores, Darlene C.; Beck, Paulo; Freitag, Rogerio A.; Brondani, Sergio; Cunico, Wilson; Bonacorso, Helio G.; Zanatta, Nilo Synthesis, 2002 , # 16 p. 2353 - 2358

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Citation Number: 36

Abstract

Abstract A series of twelve 5-bromo [5, 5-dibromo]-4-methoxy-1, 1, 1-trihalo-3-alken-2-ones 5a-d, 6a-d, 7a, 9a, 10a and 6-bromo-5-methoxy-1, 1, 1, 2, 2-pentafluoro-4-hexen-2-one (8a) were synthesized in high purity and good yields (70-95%) by the regiospecific allylic bromination of 4-methoxy-1, 1, 1-trihalo-3-alken-2-ones 1a-d, 2a-d, 3a or 5-methoxy-1, 1, 1, 2, 2-pentafluoro-4-hexen-2-one (4a), respectively, with bromine followed by addition of ...