Tetrahedron

Efficient combination of task-specific ionic liquid and microwave dielectric heating applied to one-pot three component synthesis of a small library of 4-thiazolidinones

J Fraga-Dubreuil, JP Bazureau

Index: Fraga-Dubreuil, Joan; Bazureau, Jean Pierre Tetrahedron, 2003 , vol. 59, # 32 p. 6121 - 6130

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Citation Number: 171

Abstract

The first report of the use of task-specific ionic liquid as synthetic equivalent of ionic liquid- phase matrice for the preparation of a small library of 4-thiazolidinones is reported in this paper. The starting (ethyleneglycol) ionic liquid-phase is functionalized in good yields with 4- (formylphenoxy) butyric acid by using usual esterification reaction conditions (DCC/DMAP as catalyst). The synthesis of the ionic liquid-phase bound 4-thiazolidinones was ...