Amination of 4-azafluorene under chichibabin reaction conditions. Some chemical transformations of 1-amino-4-azafluorene

AV Varlamov, AN Levov, F Toze, AI Chernyshev…

Index: Varlamov; Levov; Toze; Chernyshev; Davydov; Ryabov; Egorova Chemistry of Heterocyclic Compounds, 2002 , vol. 38, # 12 p. 1484 - 1490

Full Text: HTML

Citation Number: 4

Abstract

The electrophilic substitution reactions and transformations involving the methylene group at C(9) have been studied rather thoroughly for the azafluorene isomers [1]. On the other hand, nucleophilic substitution into the pyridine fragment has hardly been investigated. Only the phenylation of 3-methyl-2-azafluorene by phenyllithium in ether has been studied [2]. This reaction proceeds at the free α-carbon atom to give 3-methyl-1- phenyl-2-azafluorene. We are the first to ...