Ethaden synthesis

…, IV Yakovleva, LV Persanova, EV Aleksandrova

Index: Kochergin; Yakovleva; Persanova; Aleksandrova Pharmaceutical Chemistry Journal, 1998 , vol. 32, # 6 p. 327 - 330

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Abstract

Ethaden, or 6-amino-8-(13-hydroxyethylamino)purine hy- drobromide hydrate (Xa), is an original Russian drug used as a stimulator of reparative processes in the human organism. The drug is administered in cases of ulceration in the stomach and duodenum, thermal and radiation skin damage, and leuk- openia [ 1 - 3]. Ethaden as a chemical compound was obtained in the form of free base (X) by interaction of 8-bromoadenine with 2-aminoethanol [4]. Because ...