Organic letters

Direct Synthesis of NH Carbazoles via Iridium (III)-Catalyzed Intramolecular C–H Amination

C Suzuki, K Hirano, T Satoh, M Miura

Index: Leslie, Colin P.; Fabio, Romano Di; Bonetti, Francesca; Borriello, Manuela; Braggio, Simone; Forno, Giovanna Dal; Donati, Daniele; Falchi, Alessandro; Ghirlanda, Damiano; Giovannini, Riccardo; Pavone, Francesca; Pecunioso, Angelo; Pentassuglia, Giorgio; Pizzi, Domenica A.; Rumboldt, Giovanna; Stasi, Luigi Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 4 p. 1043 - 1046

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Citation Number: 30

Abstract

... Expectedly, the reactions of 2′-substituted 1n–p gave exclusively 4-substituted carbazoles 2n–p in good yields (entries 14–16). ... Thus, treatment of 1a (0.25 mmol) with 3,6-di-tert-butyl- (2w) and 3,6-dichlorocarbazoles (2x) (0.25 mmol) in the presence of [Cp*IrCl 2 ] 2 (0.01 mmol ...