Heterocycles

Synthesis, crystal structure determination and antiproliferative evaluation of novel benzazoyl benzamides

…, B Kaitner, M Kralj, K Ester, G Karminski-Zamola

Index: Starcevic, Kristina; Caleta, Irena; Cincic, Dominik; Kaitner, Branko; Kralj, Marijeta; Ester, Katja; Karminski-Zamola, Grace Heterocycles, 2006 , vol. 68, # 11 p. 2285 - 2299

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Citation Number: 17

Abstract

Résumé/Abstract A series of benzazoyl-benzamides containing different substituents (7-17) were synthesized by condensation of 2-aminobenzazole derivatives (3a-6) with p- substituted benzoyl chlorides. All compounds were characterized by IR, 1 H and 13 C NMR, MS and elemental analysis. Crystal structure was determined for the compound (9). Some of the new synthesized compounds (7-17) were screened for antitumor activities. Based on ...