Electrophilic aromatic substitution. 5. A kinetic study of Friedel-Crafts acylation in nitromethane

…, GL Delker, NJ Baker, JF Feigon, D Ono…

Index: DeHaan, Franklin P.; Covey, William D.; Delker, Gerald L.; Baker, Nancy J.; Feigon, Juli F.; et al. Journal of Organic Chemistry, 1984 , vol. 49, # 21 p. 3959 - 3963

Full Text: HTML

Citation Number: 11

Abstract

Noncompetitive kinetic studies were made of the AlClpxtalyzed reaction of 2, 4- dichlorobenzoyl chloride with benzene and with toluene in nitromethane at 20" C. The reaction appears to follow the kinetic expression: rate=(k/[AlC13],)[ArH][acid chloride][AlC13]. The kT/kB= 472 84 and product isomer distributions (8.4* 0.3)% ortho,(0.43 0.02)% meta, and (91.2* 0.3)% para are in good agreement with the Brown selectivity ...