Abstract Conversion of 4, 4′-dimethyl-2, 2′-bipyridine to 4-hexadecyl-4′-methyl-2, 2′- bipyridine, 4-heptadecyl-4′-methyl-2, 2′-bipyridine, and 4, 4′-diheptadecyl-2, 2′- bipyridine by treatment with lithium diisopropylamine followed by an appropriate alkyl bromide is reported.