Tetrahedron letters

1, 3-Dipolar cycloaddition of nitrile oxides to 1-phenylsulfonyl-1, 3-butadienes: synthesis of 3-(4, 5-dihydroisoxazol-5-yl) pyrroles

SH Hwang, MJ Kurth

Index: Hwang, Sung Hee; Kurth, Mark J Tetrahedron Letters, 2002 , vol. 43, # 1 p. 53 - 56

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Citation Number: 21

Abstract

Novel heterocyclic compounds containing the 3-(4, 5-dihydroisoxazol-5-yl) pyrrole ring system were synthesized in good yields (66–78%) by regioselective 1, 3-dipolar cycloaddition of nitrile oxides to 1-phenylsulfonyl-1, 3-dienes followed by Barton–Zard pyrrole annulation.