A structure–taste study of arylsulfonyl (cyclo) alkanecarboxylic acids

V Lysiak, A Ratajczak, A Mencel, K Jarzembek…

Index: Lysiak, Violetta; Ratajczak, Aleksander; Mencel, Agnieszka; Jarzembek, Krystyna; Polanski, Jaroslaw Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 3 p. 671 - 675

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Citation Number: 4

Abstract

A number of sweeteners contain a sulfonyl group. In our current search for new glucophores several new compounds containing such group were obtained. A series of novel 1- phenylsulfonylcyklohexanecarboxylic acids and 2-arylsulfonylalkanecarboxylic acids was obtained and evaluated for their sweet taste quality. It has been found that methyl substituents are of the key importance for the activity of these compounds.