Estrogen receptor β ligands: Design and synthesis of new 2-phenyl-isoindole-1, 3-diones

JW Ullrich, RJ Unwalla, RR Singhaus, HA Harris…

Index: Ullrich, John W.; Unwalla, Rayomand J.; Singhaus Jr., Robert R.; Harris, Heather A.; Mewshaw, Richard E. Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 1 p. 118 - 122

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Citation Number: 9

Abstract

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... The design, synthesis, and biological evaluation of the 2-phenyl-isoindole-1,3-diones will be discussed. Detailed modeling studies with X-ray support were used to understand the ligand binding orientation and observed selectivity. ... The design, synthesis and biological ...