Palladium??Catalyzed Cascade Cyclization of Ynamides to Azabicycles

…, CD Campbell, OT Holton, CA Russell…

Index: Greenaway, Rebecca L.; Campbell, Craig D.; Holton, Oliver T.; Russell, C. Adam; Anderson, Edward A. Chemistry - A European Journal, 2011 , vol. 17, # 51 p. 14366 - 14370

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Citation Number: 30

Abstract

Nitrogen-containing bicyclic heteroaromatics are ubiquitous in organic chemistry, featuring in countless natural products and drugs.[1] Their importance is evidenced by the multitude of synthetic routes that have been developed to access such structures,[2] the majority of which use a prefunctionalized benzene ring as a nucleus for heterocycle annulation—an approach that intrinsically suffers from a reduced ability to diversify the benzenoid portion of the ...