e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
PH bond activation of primary phosphine-boranes: Access to α-hydroxy and α, α′-dihydroxyphosphine-borane adducts by uncatalyzed hydrophosphination of …
Primary P-phenyl and P-methyl phosphine-boranes 1 and 2 are prepared by complexation of the free phosphines with BH3· SMe2. They are stable and can be purified by distillation. Under basic conditions, they lead selectively to secondary alkylphosphine-boranes and under neutral conditions to the corresponding mono-and bis-hydroxyphosphine-boranes 5 and 6. All these new compounds are purified by chromatography on silica gel. A ...
