Genotoxicity of aminohydroxynaphthoquinones in bacteria, yeast, and Chinese hamster lung fibroblast cells

LF da Costa Medina, CM Viau, DJ Moura, J Saffi…

Index: da Costa Medina, Luis Fernando; Viau, Cassiana Macagnan; Moura, Dinara Jaqueline; Saffi, Jenifer; Stefani, Valter; Brandelli, Adriano; Henriques, Joao Antonio Pegas Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2008 , vol. 650, # 2 p. 140 - 149

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Citation Number: 11

Abstract

There are few studies on the biological activity of aminohydroxy derivates of 1, 4- naphthoquinone (1, 4-NQ) on prokaryotic and eukaryotic cells. We determined the mutagenic activity of 5-amino-8-hydroxy-1, 4-naphthoquinone (ANQ) and 5-amino-2, 8- ...