Ultrasonics promoted synthesis of thiazolidinones from 2-aminopyridine and 2-picolilamine

…, J Bosenbecker, BB Drawanz, PD Neuenfeldt…

Index: Gouvea, Daniela P.; Bareno, Valeria D.O.; Bosenbecker, Juliano; Drawanz, Bruna B.; Neuenfeldt, Patricia D.; Siqueira, Geonir M.; Cunico, Wilson Ultrasonics Sonochemistry, 2012 , vol. 19, # 6 p. 1127 - 1131

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Citation Number: 38

Abstract

The efficient multicomponent synthesis of thiazolidinones from the reaction of arenealdehydes, mercaptoacetic acid and 2-picolilamine or 2-aminopyridine under ultrasound irradiation are reported. The reaction with 2-aminopyridine needs a Lewis acid catalysis to afford the corresponding 2-aryl-3-(pyridin-2-yl)-1, 3-thiazolidin-4-ones. All novel compounds were identified and characterized by 1H and 13C NMR spectra. Applying the ...