The invention and development of highly enantioselective catalytic reactions with a low catalyst loading is one of the current challenges in organic chemistry. One such area is the activation of reactants by Lewis base/acid pairing.[1] Especially attractive in this regard is the enantioselective allylation of carbonyl compounds (Sakurai–Hosomi reaction) with allylmetals to give chiral homoallylic alcohols that can be used as building blocks in the ...
