e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Synlett
A multi-task palladium catalyst involved in Heck-Reduction-Cyclization sequences for the preparation of 4-benzyl-1, 2-dihydroisoquinolin-3-ones: An unusual …
Abstract A mixed homogeneous-heterogeneous catalysis that exploits a multi-task palladium catalyst has been developed for one-pot sequential Heck-reduction-cyclization (HRC) reactions leading to novel 4-benzyl-1, 2-dihydroisoquinolin-3-ones. The HRC sequence requires mild conditions and allows the separation of the palladium residues under the form of an in situ generated Pd (0)/C catalyst by simple filtration. The homemade and recovered ...