Enantioselectivity increases with reactivity: electronically controlled asymmetric addition of diethylzinc to aromatic aldehydes catalyzed by a chiral pyridylphenol

H Zhang, F Xue, TCW Mak…

Index: Zhang, Huichang; Xue, Feng; Mak; Chan, Kin Shing Journal of Organic Chemistry, 1996 , vol. 61, # 23 p. 8002 - 8003

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Citation Number: 93

Abstract

Achieving enantioselective reactions through a catalytic process is recognized as one of the most important and challenging problems in organic synthesis, and therefore it has received much attention. Enormous progress has been made in this area during the past decade. 1 However, the factors governing enantioselectivity remain the subject of speculation even in reactions that have been extensively studied. 2 Enantioselectivity in catalytic asymmetric ...