Propargylic alcohols and esters are versatile building blocks as they allow for facile conversion to a variety of functional groups in the synthesis of allenes, lactones, and heterocycles, which are part of biologically active molecules [ 1 1. (a) Stang , PJ ; Diederich , F. (Eds.). Modern Acetylene Chemistry ; VCH : Weinheim , Germany , 1995 ; (b) Shi Shun , ALK ; Tykwinski , RR Synthesis of naturally occuring polyynes. Angew. Chem. Int. Ed. 2006, 45, 1034–1057 .
