Tetrahedron letters

Synthesis of 2-fluoroabscisic acid: A potential photo-stable abscisic acid

BT Kim, YK Min, T Asami, NK Park, OY Kwon, KY Cho…

Index: Kim, Bum Tae; Min, Yong Ki; Asami, Tadao; Park, No Kyun; Kwon, Oh Young; Cho, Kwang Yun; Yoshida, Shigeo Tetrahedron Letters, 1997 , vol. 38, # 10 p. 1797 - 1800

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Citation Number: 23

Abstract

Novel fluorinated abscisic acid (ABA) analogs were synthesized by introducing fluorine through the Wittig reaction of α-ionone derivatives with triethyl phosphono-2-fluoroacetate. Molecular orbital calculations showed that the introduction of fluorine at the 2 position stabilized the configuration of the side chain.