Tetrahedron: Asymmetry

Enzyme assisted synthesis of enantiomerically pure myo-inositol derivatives-Chiral building blocks for inositol polyphosphates

P Andersch, MP Schneider

Index: Andersch, P.; Schneider, M. P. Tetrahedron: Asymmetry, 1993 , vol. 4, # 10 p. 2135 - 2138

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Citation Number: 54

Abstract

Abstract Using a short and facile synthetic protocol involving highly selective, regio-and enantioselective enzymatic esterifications as key reaction steps, readily available myo- inositol is converted into optically pure ID-1-O-butyryl-4, 6-O-dibenzoyl-myo-inositol (−)-5, a selectively protected central intermediate for the preparation of numerous inositol phosphates.