A synthesis of echinopine B

…, MS Dowling, CD Vanderwal

Index: Michels, Theo D.; Dowling, Matthew S.; Vanderwal, Christopher D. Angewandte Chemie - International Edition, 2012 , vol. 51, # 30 p. 7572 - 7576

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Citation Number: 19

Abstract

The synthesis of natural products of unprecedented structure can drive innovation in strategy and provide opportunities to test the limits of new methodology; therefore, it remains a worthy venture even when the targets are not yet known to possess important biological activity. In that context, we felt that the synthesis of the structurally unusual echinopines (Scheme 1) was warranted for the opportunity to evaluate metal-catalyzed polycyclizations ...