Asymmetric Michael reactions of aminocarbene complex anions

BA Anderson, WD Wulff, A Rahm

Index: Andersen, Benjamin A.; Wulff, William D.; Rahm, Annette Journal of the American Chemical Society, 1993 , vol. 115, # 11 p. 4602 - 4611

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Citation Number: 69

Abstract

Abstract: The first Michael addition reactions of the anions of aminocarbene complexes to a, b-unsaturated carbonyl compounds are reported. Unlike their corresponding amide enolates, these anions give exclusive 1, 4-addition to a number of enones. For chiral complex 27, it was shown that the formation of the 1, 4-addition product is not reversible and that the initial 1, 4-addition is thus kinetically controlled. The anions of aminocarbene ...

~62%

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Revised Structure, Total Synthesis, and Absolute Configurati...

[Ibarra, Carlos Alvarez; Arias, Selma; Fernandez, Maria J.; Sinisterra, Jose V. Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1989 , p. 503 - 508]

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