Tetrahedron Letters

Cyclononitols: a flexible synthetic approach towards nine-membered carbasugar analogues

G Mehta, K Pallavi, S Katukojvala

Index: Mehta, Goverdhan; Pallavi, Kotapalli; Katukojvala, Sreenivas Tetrahedron Letters, 2009 , vol. 50, # 31 p. 4519 - 4522

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Citation Number: 11

Abstract

The impressive advances in the area of carbohydrate mimetics in recent years, have been largely prompted by their ability to function as glycosidase inhibitors and have led to the conception and synthesis of a wide variety of novel structures. 1 The commonly pursued approach towards the design of glycosidase inhibitors has been to generate structures that resemble monosaccharides in shape, size and functionality and to mimic the geometry and charge in the transition ...