Pyridyl and thiazolyl bisamide CSF-1R inhibitors for the treatment of cancer

DA Scott, BM Aquila, GA Bebernitz, DJ Cook…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 18, # 17 p. 4794 - 4797

Full Text: HTML

Citation Number: 26

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... Compounds were prepared via the routes shown in Scheme 1, varying the sequence of reactions to install the thiazole or the phenyl ring at the end of the synthesis 22 (pyridyl examples were prepared using similar chemistry). ...