Tetrahedron letters

Synthesis of chemically reactive analogues of AZT and their biological evaluation against HIV

SL Schreiber, N Ikemoto

Index: Schreiber, Stuart L.; Ikemoto, Norihiro Tetrahedron Letters, 1988 , vol. 29, # 26 p. 3211 - 3214

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Citation Number: 43

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Several 3'-deoxythymidine analogues were prepared and tested against HIV. The choice of analogues was based on their possible covalent binding to the enzyme reverse transcriptase. ... Several 3'-deoxythymidine analogues, including the hydroperoxide 4, were prepared and tested ...