Kinetics of N??Formylation of Piperidine and Related Compounds

L Maat, M Peereboom

Index: Maat, L.; Peereboom, M. Bulletin des Societes Chimiques Belges, 1983 , vol. 92, # 10 p. 877 - 880

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Abstract

Abstract The kinetics of the N-formylation of piperidine and 3-methylpiperidine with chloral hydrate and 1, 2, 3, 4-tetrahydroisoquinoline with chloral in toluene, have been investigated. The reactions are first order in both reactants. The formylation of piperidine is faster than that of 1, 2, 3, 4-tetrahydroisoquinoline and somewhat slower than that of 3-methylpiperidine.