Two 2-fluorophenyl-5-substitued cyclopropyl-1, 3, 4-oxadiazoles (IIIa–b) with cis/trans isomers were synthesized from the corresponding hydrazide (Ia) and aroyl chlorides by two- step reactions. Six asymmetrical 2-(2, 4-dichloro-5-fluorophenyl)-5-aryl-1, 3, 4-oxadiazoles (IIIc–h) were obtained by one step reaction of 2, 4-dichloro-5-fluorobenzoic acid hydrazide (Ic) with the corresponding aromatic carboxylic acid in the presence of phosphorus ...
