Heterocycles

Convenient access to 3, 4, 5-trisubstituted pyridines

A De Munno, V Bertini, N Picci, F Iemma, M Pocci

Index: Heterocycles, , vol. 43, # 9 p. 1893 - 1900

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Citation Number: 2

Abstract

The reaction of 3,5-dichloro-4-pyridinecarbonitrile towards nucleophilic substitution of chlorine atoms and nucleophilic addition to the cyano group has been studied in presence of different nucleophiles and solvents in order to evidence the best conditions for the synthesis of 3,4, ...