Abstract A convenient method for synthesis of novel 1-[pyrimidinyl], 1-[1, 3, 5-triazin-2- carbonyl], and 1-[thiazol-5-carbonyl] derivatives of 3-thioxo-diaziridine 1, 3, 5, and 7 from corresponding hydrazides, CS2, and KOH is elaborated. The highest reaction yield was observed when these initial reagents were taken in molar ratio of 1: 1.7: 2.0, respectively. By alkylation of compounds 1, 3, 5, and 7 that proceeds exclusively at sulfur atom, the 3- ...