3-Mercapto-1, 2, 4-triazoles and N-acylated thiosemicarbazides as metallo-β-lactamase inhibitors

WM Hussein, P Vella, NU Islam, DL Ollis…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 1 p. 380 - 386

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Citation Number: 30

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... The imipenemase (IMP-1) MBL from P. aeruginosa has been identified in many reported cases of antibiotic resistance in medical facilities world-wide, leading to diseases such as pneumonia, bacteriemia, urosepsis and wound ...