Access to 2??Aminopyridines–Compounds of Great Biological and Chemical Significance

JL Bolliger, M Oberholzer…

Index: Bolliger, Jeanne L.; Oberholzer, Miriam; Frech, Christian M. Advanced Synthesis and Catalysis, 2011 , vol. 353, # 6 p. 945 - 954

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Citation Number: 21

Abstract

Abstract 2-Aminopyridines are key structural cores of bioactive natural products, medicinally important compounds, and organic materials and thus, extremely valuable synthetic targets. The few reported 6-substituted 2-aminopyridines and the lack of flexible, efficient and general applicable methods for their synthesis demonstrates the urgent need of new methods for their preparation. Reactions between 2, 6-dibromopyridine and primary or ...