e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Synthesis
Chemistry of 3-Hydroxypyridine Part 4: Synthesis of 2-and 2, 3-Substituted 5-[Fluoro (chloro) alkoxy] pyridines via 5-Hydroxy-2-(4-nitrophenylazo) pyridines
All reagents were of commercial quality from freshly opened containers. Compounds la and b were purchased from Aldrich Chemical Co and were pure according to 1H-NMR spectra. Melting points were taken using a Buechi SM 20 melting point apparatus and are uncorrected. Microanalyses were performed in the analytical department of Hoechst AG. 100 MHz 1H-NMR-and 94.2 MHZ 19F-NMR-spectra were recorded on a Bruker AM 100 ...