Application of Polymer??Supported Triphenylphosphine and Microwave Irradiation to the Palladium??Catalyzed Cyanation of Aryl Triflates

…, AJ Zych, DM Jenkins, HJ Wang, ZJ Chen…

Index: Srivastava, Rajiv R.; Zych, Andrew J.; Jenkins, David M.; Wang, Hong-Jun; Chen, Zhen-Jia; Fairfax, David J. Synthetic Communications, 2007 , vol. 37, # 3 p. 431 - 438

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Citation Number: 15

Abstract

Abstract A variety of aryl nitriles were prepared in excellent yield from the palladium (II) acetate–catalyzed cross??coupling of aryl triflates and zinc cyanide under microwave irradiation conditions. To facilitate purification, polymer??supported triphenylphosphine was used as the palladium ligand. Comparison to the corresponding thermal conditions revealed much shorter reaction times with comparable yields.