e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
New Reactions of N??tert??Butylimines; Formation of N??Heterocycles by Methyl Radical Elimination on Flash Vacuum Thermolysis of N??Benzylidene??and N??(2?? …
Abstract Thermal reactions of N-benzylidene-and N-(2-pyridylmethylidene)-tert-butylamines (5 and 13) under FVT conditions have been investigated. Unexpectedly, at 800 C, compound 5 yields 1, 2-dimethylindole and 3-methylisoquinoline. In the reaction of 13 at 800 C, 3-methylimidazo [1, 5-a] pyridine was obtained as the major product. Mechanisms of these reactions have been proposed on the basis of DFT calculations. Furthermore, UV- ...