e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Mechanism of direct side-chain acylamination and aminoarylation of 2-and 4-picoline 1-oxides
RA Abramovitch, DA Bramovitch…
Index: Abramovitch, Rudolph A.; Abramovitch, Dorota A.; Tomasik, Piotr Journal of the Chemical Society, Chemical Communications, 1981 , # 11 p. 561 - 562
The isolation of radical coupling products and the observation of appropriate CINDP signals suggest that most of the title reactions proceed by homolysis of the anhydro-bases (4) or (9) followed by radical recombinations; a diaza-oxy-Cope rearrangement may still account for the formation of α-acylamination products.
