Total synthesis of an antitumour antibiotic,(±)-reductionmycin

M Ojika, H Niwa, Y Shizuri, K Yamada

Index: Ojika, Makoto; Niwa, Haruki; Shizuri, Yoshikazu; Yamada, Kiyoyuki Journal of the Chemical Society, Chemical Communications, 1982 , # 11 p. 628 - 629

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Citation Number: 7

Abstract

Reductiomycin (1) is an antibiotic, which shows activity have shown by chemical and spectroscopic data that the against tumours, l gram-positive bacteria, 2 fungi, 2 and New- structure is (1), 4 and we have now confirmed this by synthesis. castle disease virus. 2 While the structure of reductiomycin has Oxidation of 3-hydroxymethylfuran (2) 5 with lead (1v) been reported to be (12), based on X-ray~ rystallography,~ we acetate (AcOH, room ...