Abstract Ruthenium porphyrins (particularly [Ru (2, 6-Cl 2 tpp) CO]; tpp= tetraphenylporphinato) and RuCl 3 can act as oxidation and/or Lewis acid catalysts for direct C-3 alkylation of indoles, giving the desired products in high yields (up to 82% based on 60– 95% substrate conversions). These ruthenium compounds catalyze oxidative coupling reactions of a wide variety of anilines and indoles bearing electron-withdrawing or ...
[Perrin, Charles L.; Ohta, Brian K.; Kuperman, Joshua; Liberman, Jordan; Erdelyi, Mate Journal of the American Chemical Society, 2005 , vol. 127, # 26 p. 9641 - 9647]
