Binuclear derivatives of phenylmercaptoacetic acid and their tris (2-hydroxyethyl) ammonium salts. Effect on the functional activity of thrombocytes

GG Levkovskaya, YI Kryukova, YA Moskvichev…

Index: Levkovskaya, G. G.; Kryukova, Yu. I.; Moskvichev, Yu. A.; Mironov, G. S.; Kryukova, G. G.; et al. Pharmaceutical Chemistry Journal, 1984 , vol. 18, # 4 p. 249 - 253 Khimiko-Farmatsevticheskii Zhurnal, 1984 , vol. 18, # 4 p. 431 - 435

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Abstract

Moreover, the dominating significance of the oxidation of arachidonic acid in the aggregation of thrombocytes has recently been revealed [5-7]. It has been established that the use of inhibitors of the free-radical oxidation of lipids is promising for the treatment of disruptions of the aggregation of thrombocytes. We have synthesized the following phenylmercaptoacetic acid derivatives: gococHt-X-CEtCOOH (7-~) z: x=-s-@--@ s-~ 2: x=- ...