Tetrahedron letters

A convenient method for the preparation of primary amines using tritylamine

V Theodorou, V Ragoussis, A Strongilos, E Zelepos…

Index: Theodorou, Vassiliki; Ragoussis, Valentine; Strongilos, Alexandros; Zelepos, Evangelos; Eleftheriou, Argyro; Dimitriou, Maria Tetrahedron Letters, 2005 , vol. 46, # 8 p. 1357 - 1360

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Citation Number: 23

Abstract

A simple method for the preparation of primary amines by treating N-tritylamines with trifluoroacetic acid has been established. The N-tritylamines were prepared by the reaction of alkyl halides or alkyl p-toluenesulfonates with tritylamine, or by the reaction of alkyl bromides with lithium tritylamide.